Production of pharmaceutical proteins by transgenic animals
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چکیده
منابع مشابه
Production of pharmaceutical proteins by transgenic animals.
Proteins started being used as pharmaceuticals in the 1920s with insulin extracted from pig pancreas. In the early 1980s, human insulin was prepared in recombinant bacteria and it is now used by all patients suffering from diabetes. Several other proteins and particularly human growth hormone are also prepared from bacteria. This success was limited by the fact that bacteria cannot synthesize c...
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Polyclonal antibodies collected from the blood of animals and humans experimentally immunised or spontaneously immunised respectively can be injected into patients to protect them against pathogens, toxins, tumours etc. This approach is severely limited by the availability of human polyclonal antibodies of interest. Moreover, polyclonal antibodies from animals are recognised as antigens by pati...
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ژورنال
عنوان ژورنال: Comparative Immunology, Microbiology and Infectious Diseases
سال: 2009
ISSN: 0147-9571
DOI: 10.1016/j.cimid.2007.11.005